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Emirates named Worlds Best Airline at Skytrax World Airline Awards 20

first_imgEmirates named World’s Best Airline at Skytrax World Airline Awards 2016Emirates was today named the World’s Best Airline 2016 at the prestigious Skytrax World Airline Awards 2016, in addition to scooping up the awards for World’s Best Inflight Entertainment for a record 12th consecutive year, and Best Airline in the Middle East.Based on the results of the largest airline passenger satisfaction survey in the industry, the World’s Best Airline Awards are considered a global benchmark of airline excellence. This year’s Skytrax awards were based on a total of 19.2 million completed surveys covering 280 airlines, by customers hailing from more than 104 countries. The Skytrax survey measures quality standards across 41 key performance indicators of front-line products and services in the airline industry.This is the fourth time Emirates has won the top accolade since the airline awards were introduced 15 years ago; the airline won the first ever Skytrax World’s Best Airline in 2001, again in 2002 and in 2013. In total, Emirates has won a total of 20 Skytrax World Airline Awards since 2001.Sir Tim Clark, President Emirates Airline, said: “We are honoured to be recognised by the prestigious Skytrax awards. Emirates has always put our customers at the heart of what we do, and we work hard to deliver the very best experience possible to our customers at every touchpoint, every day, all around the world. We constantly invest in our product and services, both on the ground and in the air. We listen carefully to our customers, and then relentlessly challenge ourselves to deliver and exceed expectations. The fact that these awards are based on the direct feedback from passengers is gratifying and wonderful recognition for all of the hard work that’s gone into creating the Emirates experience.”Commenting on the Award, Edward Plaisted, CEO of Skytrax said: “This fourth World’s Best Airline title for Emirates is a fantastic achievement and true testament to the airline’s popularity. To satisfy customers from such a wide and diverse passenger base is not an easy task, but Emirates continues to gain superlative feedback from customers for its product and service offering from the front to the back of the aircraft. The IFE that Emirates provides is a continued focal point for passenger praise and it is important to note that customers were not only impressed with the programming but also the superior hardware standards, particularly for the A380 fleet.”Emirates is the world’s largest international airline, with an extensive network that has grown to offer its customers a choice of 154 destinations in 81 countries across six continents, with convenient connections through its hub in Dubai. The airline operates one of the world’s youngest modern wide-body fleets. These aircraft are not only more efficient to operate, but are also more comfortable for passengers to fly in – enabling Emirates to install and offer the latest onboard products.Over the past 12 months, Emirates has rolled out a number of new product and service investments, including the unveiling of a new 777-300ER Business Class seat; expanding its global Emirates Lounge network to 39 with the opening of new facilities in Cape Town; launching new children’s toys and activity kits both on board and in the lounges and new amenity kit bags for First and Business Class travellers, investing over US$140 million in its wine programme for all cabin classes in 2015 alone, and much more.On most of Emirates’ fleet, including all of its A380 aircraft, passengers in all classes can enjoy unprecedented Wi-Fi connectivity. On average, over a quarter of all passengers use the internet during their flight. This figure increases to half on flights over 12 hours. EmiratesSource = Emirateslast_img read more

ErrorOK ErrorOK

first_imgErrorOK… ErrorOK Grace expects Greinke trade to have emotional impact Former Cardinals kicker Phil Dawson retires Comments   Share   Arians was willing to give Glennon the chance to add his name to the list instead of ensuring the Bucs could do nothing more than tie. There’s no guarantee Arizona would have scored a touchdown, but as long as Palmer or anyone else on the Cardinals offense didn’t turn the ball over, that same Jay Feely field goal would have been there on the next play. I don’t know who or why, but Arians made it abundantly clear when the game is on the line he doesn’t yet trust his offense. Top Stories In 2009, Bill Belichick made the controversial decision to go for it on 4th-and-2 from the Patriots’ 28-yard line up six in a high-profile regular season game against the Indianapolis Colts. The move backfired, but Belichick decided he wanted to try and win or lose the game with the ball in Tom Brady’s hands instead of entrusting a leaky defense. The Cardinals-Buccaneers game obviously didn’t have the same national profile as Pats-Colts, but Arians’ play call does tell you what he truly thinks about his offense just as Belichick’s did about his defense. The Cards’ head coach was willing to take a risk of losing the game instead of giving Palmer the opportunity to put the ball in the end zone. Circumstances have to be taken into account. The way the second half went for the Tampa Bay offense plus the fact they had Mike Glennon, a rookie quarterback, making his first start, I do understand the logic behind Arians’ move. With that being said, just because Glennon is inexperienced doesn’t mean he wasn’t capable of moving the ball down the field to tie the game with a field goal or win the game with a touchdown. Rookie quarterbacks EJ Manuel and Geno Smith have both led game-winning drives with under two minutes left in the fourth quarter in the first four games of their careers. The 5: Takeaways from the Coyotes’ introduction of Alex Meruelo Derrick Hall satisfied with D-backs’ buying and selling With one single play call, we learned something about what Arizona Cardinals head coach Bruce Arians thinks about his football team. On 3rd and goal from the 7-yard line with less than two minutes left in a 10-10 game, Arians had quarterback Carson Palmer line up a field goal instead of trying to score a touchdown. When things are tight and the game is one the line, it is human nature to make decisions based on what you trust most. – / 19last_img read more

In This Issue Yellens Friday words still dom

first_imgIn This Issue. * Yellen’s Friday words still dominating currencies & metals. * Yen falls another whole figure. * Singapore 1st QTR GDP is strong! * Doesn’t anyone see what I see? And Now. Today’s A Pfennig For Your Thoughts. The CBR Sends The Ruble To The Woodshed. Good day..  And a Wonderful Wednesday to you! Well, those dangerous storms continue in the South. Last night, I sent a text to my younger sister, who lives with my other younger sister, just outside of Houston, to check and make sure they were safe. Not that I know what I would have done if she said they weren’t safe, but, I felt I needed to do that, being their older brother. It’s been quite the storm filled spring here in the U.S., eh?  Usually, our area is right smack dab in the middle of that stuff, but not this year, as the jet stream has dropped to the south. But not today, it appears the nasty stuff is headed straight up Highway 44 to St. Louis, the normal route for spring storms. UGH!   The official start to Spring doesn’t come until the middle of next month, although the thought that summer began with Memorial Day, usually registers more with people.. June is going to be quite interesting for the Eurozone, the euro, and Greece, as Greece is scheduled to make loan payments to the IMF on June 5th, 12th, 16th and 19th. WOW! I’m not sure what Greece can do about all this, except to accept the austerity measures and secure the loans, or, just walk away, default, and cause chaos. I’ve written about how if I were the Eurozone leaders I would just say, “here it is, take it or leave it”, and if Greece decided to leave it, then so be it. For, to me, they are the slowest Buffalo. And to make the herd faster you must allow the slowest Buffalo to be killed.   Hey! In all seriousness, I learned the slowest Buffalo theory from Cliff Clavin! So there! The dollar rally seems to have been a little overdone, and the green/peachback is generally weaker this morning. The Japanese yen seems to be really slipping and sliding along the slippery slope these past couple of days. Yesterday, I told you how the yen had slipped from 121 to 122, well today it’s 123. It’s not the same old names, but the same of titles of officials that are talking about, “how excessive FX moves are not warranted” and stuff like that. But, they have no one to blame but themselves for these sweeping moves taking place with yen, as it’s these same leaders that have gone about adding stimulus and generally attempting to get yen weaker to promote economic growth. It’s a classic case of being careful of what you wish for, as you may get your wish! The euro has regained some lost ground, but it has been trading all over the place lately with no general direction carved out. Some might say that the 3-cent drop in the euro from Friday morning to Tuesday morning, as a clear direction downward, but I would stop them and say that the euro has bounced twice now after falling below 1.09, so be careful here. The Eurozone/ Greek talks will begin again today. I don’t hold out a lot of hope here today. In the U.K. today, the Queen will speak and set out the government’s policy for the parliamentary sessions. The markets will be looking for any sign that the Queen is behind this latest move by parliament to leave the European Union. They call this a Brexit.   So, now we’ve made up two words: Grexit, and Brexit. The British pound has enough to worry about, with the lack of economic growth, falling inflation and no rate hikes as promised, but apparently you can now count this little ditty. The Bank of Canada (BOC) meets today, and will make a rate decision. I don’t believe that the BOC will do anything drastic with rates. The economic performance of Canada has been a mixed bag-o-results, and with that going on, there’s no reason for the BOC to move rates in either direction. Although I would think that BOC Gov. Poloz would love to cut rates so he can join his fellow Central Bankers around the world. Shoot Rudy, if he doesn’t cut rates like the rest of the clan, what on earth would they talk about at the next cocktail party? I had a dear reader send me a note yesterday, telling me that all these moves by Central Bankers reminded him of the great Albert Einstein quote, which I now believe is my fave quote!  Einstein said, “The difference between intelligence and stupidity is that intelligence is limited”.   I think that sometimes that quote applies to me. I was such a dolt yesterday about something so mundane, but a dolt nonetheless, so, see, the dear reader believes that quote reminds him of Central Bankers, and I think it reminds me of me! HA! Well, one of the best performing currencies year to date, the Russian ruble, appears to have met its match with regards to appreciation, as the Central Bank of Russia (CBR) is gaining traction with their desire to weaken the ruble, as they feel that the ruble’s move has been too far, too fast. I think otherwise, but then I’m no Central Banker.  The chartists are now piling on the ruble, talking about how the ruble has traded through its 200-day moving avg. (DMA) and it could be the start of a bearish trend in the ruble that could take it from the current level 51.50 to 56. For the record, the CBR has cut rates, as if that wasn’t expected given the CBR boosted rates to 17% to defend the ruble last year, and the CBR has apparently intervened, selling rubles in the market to weaken it.   Longtime readers know how much I dislike Central Banks sticking their hands in the currency cookie jar, so not that long ago I smiled when thinking of the ruble, and now my smile has turned upside down, because of the CBR’s actions. UGH!  Can I get a bone thrown to me here? The Chinese renminbi / yuan was pushed weaker overnight by the Peoples Bank of China (PBOC). I’m somewhat surprised by that move, given the news last night from the SWIFT payments people that the renminbi / yuan has become Asia’s most-active currency for payments in China and Hong Kong. Get this. The renminbi / yuan accounts for 31% of the region’s payments, up from 7% in April of 2012..   Now, most people don’t see this as BIG News. But I do. just like yesterday, when I told you about the SGE Gold Fund, no one else talked about it, because they didn’t see it for what it was, another brick in the wall of removing dollar relevancy. And this news? Well, here’s how I look at it, folks. China needs a wider distribution of their currency, and to get that, they need dealers to begin to make markets in the currency, and they also need for importers and exporters to begin to make payments using the renminbi / yuan so the distribution begins to spread out. So, for now it’s Asia that China has cornered the payments, and next it will be what region? Oh, there will be another region, and then another region. Because that’s what China wants. You know, there are tons of articles and reports out there that talk about deflation, and how Central Banks are fighting deflation, and would rather see “controlled inflation” as if that’s really a thing to strive for.  But no one ever talks about where the deflation came from?  Well, let’s take a quick look at the poster child for deflation. Japan. then switch over the U.S. and then to the Eurozone, and the U.K.  what do all of these countries have in common. Large Debts.. That’s what. So guess where deflation comes from in my mind? The deflation comes from the rise in the cost of government in addition to the collapse in leverage. As governments with power turn to extracting more from the people rather than weak government.  Well, there’s no sign of deflation at Disney World. Yesterday’s Five Minute Forecast (The 5)  talked about this, and it caught my eye, so I’ll borrow some of their stuff here.   No worries, I’ll give it back to them when I’m finished! HA!   So, Disney just announced that tickets for Disney World in Florida had increased to “just $100”.    That’s a far cry from what tickets cost in 1971, when it opened.. $3.50.   So, the increase of ticket prices by decade has gone like this. 1971 $3.50, 1981 $9.50, 1991 $33.00, 2001 $48.00, 2011 $85.00 and 2015 $105.     YIKES! Talk about inelastic demand!     So, here are my thoughts on this. The fact that still have families heading to Disney World, when everything around them hurts, like Retail Sales, 6,000 Retail Stores to close this year, and gas sales not being the ka-bang to the economy that everyone thought, tells me a lot. It tells me that it’s like a one last time. You know a star shines the brightest right before it burns out, thing. Well, Gold is down again today, and has now fallen below the $1,190 figure. losing touch with $1,200 as the days go by.  I told you yesterday how Fed Chair, Janet Yellen’s speech on Friday afternoon had really deep sixed Gold, by renewing the thought that a rate hike could happen in June into the minds of traders. You know, I told you yesterday, what my thoughts were on what she said. in case you missed it, you should go to the Pfennig’s website, and you can find it in the archives. just click here: www.dailypfennig.com     On a sidebar, I love the Pfennig’s website, because it gives readers the chance to go back in the archives and check out something I said in a previous Pfennig. You know, how I always say, stuff like, “I told you the other day that. “?   Well, this way you can makes certain that I did say what I said I said. And on Fridays I always post a picture of me just to remind you that I’m somewhat short, overweight, and balding, you know like the grandfather of 3 grand kids, and someone that you would want to have dinner with! HAHAHAHAHA!  Singapore printed some good economic growth data yesterday.  Sing 1st QTR GDP was given a final upward revision to 3.2% VS the advance estimate of 1.1%… Now that’s what I call a good upward revision!  So, VS the previous quarter, the Sing economy grew 3.2%, and on an annual basis, the Sing economy grew 2.6%…  And the outlook for the rest of 2015, is for an even modestly stronger growth.  So, how is Singapore growing so strongly, when the rest of the region, and the world for that matter, isn’t?  It’s called having the key ingredients being the right mix.  Pharmaceuticals, electronics, and services. Things people all over the world need and want. Have you ever heard Otis Redding’s version of the song; Try a little tenderness?  Shoot 3-Dog Night did the song, the Commitments, and probably countless others, but Otis Redding’s version will get to you.   So. the U.S. Data Cupboard yesterday, did print, as I said it would, a negative Durable Goods Orders for April, printing -0.5%… so, the first month of the 2nd QTR continues to prints some very weak data. Capital Goods Orders though rose 1%, to offset March’s -0.5% print. The S&P/ CaseShiller Home Price Index rose in March by 1.3%… Again, this housing stuff is getting overdone in my opinion, for this is nothing that looks like a long term move, but more like a blue light special sale that consumers don’t feel will be there much longer, so they have to buy now, kind of thing. And the Consumer Confidence Index rose from 94.3 to 95.4. But it’s important to look that last month’s original print was 95.2 but was revised downward to 94.3. I’ll bet a dollar to a Krispy Kreme that this print of 95.4 will get revised downward next month too. Maybe I’ll remember to talk about that next month!   But then next month is not promised to me, only today is. Today’s Data Cupboard gets a breather before heading into our Tub Thumpin’ Thursday menu. So back to no data equals no bad data for the U.S. (except housing and fabricated jobs)  So, get your rest now while you can, because we’ll head into the end of the week, and when we come back next Monday it will be June, and the data will come rolling in day after day!  To recap. The dollar’s mighty rally appears to be somewhat squelched by those traders that think the rally was overdone. The euro has regained some ground this morning, but it has really bounced around a lot lately, so watch for that.  Japanese yen has lost 3 full figures since last week, now trading to 123. Japanese leaders were vocal last night about “watching excessive moves in FX” same old rhetoric, different names, same titles.   The calls for an exit of the European Union, by the U.K. are becoming quite strong, and the Brexit as it’s called will begin to be headline news soon. Singapore posted a strong 1st QTR GDP, so what gives with Singapore being able to have economic growth when the rest of the region is struggling?  And Gold gets another day on the selling blocks, what is going on here, don’t people/ traders see the SGE Gold fund like Chuck does? Apparently not! For What It’s Worth.  Well, I found this on the Telegraph.co.uk website, because I’m always drawn to articles about debt, just like a bug to the neon light!   So, it’s not an upbeat article, it’s about debt, but I’ll try to break it to you softly. HA!   Here is the link to the whole article: http://www.telegraph.co.uk/finance/economics/11625406/The-world-is-drowning-in-debt-warns-Goldman-Sachs.html   And as usual, here are a couple of snippets for those of you, needing to get to the Big Finish quickly today! “The world is sinking under too much debt and an ageing global population means countries’ debt piles are in danger of growing out of control, the European chief executive of Goldman Sachs Asset Management has warned. Andrew Wilson, head of Europe, Middle East and Africa (EMEA), said growing debt piles around the world posed one of the biggest threats to the global economy. “There is too much debt and this represents a risk to economies. Consequently, there is a clear need to generate growth to work that debt off but, as demographics change, new ways of thinking at a policy level are required to do this,” he said. The demographics in most major economies – including the US, in Europe and Japan – are a major issue – and present us with the question of how we are going to pay down the huge debt burden. With life expectancy increasing rapidly, we no longer have the young, working populations required to sustain a debt-driven economic model in the same way as we’ve managed to do in the past.” Chuck again. So.. I’ve beaten this debt thing to a pulp over the years, but there are still economists, observers, traders, etc. that don’t think it’s that Big a thing. Well, remember what I told you above about where I believe deflation comes from. And then tie it back to this article about the debt of the developed nations. of which they all have deflation. Hmmm As we head to the currency roundup the euro has done like I feared it would this morning, giving back its gains in the two + hours I’ve been here. UGH! Currencies today 5/27/15. American Style: A$.7710, kiwi .7225, C$ .8025, euro 1.0860, sterling 1.5370, Swiss $1.0515, . European Style: rand 12.1315, krone 7.7535, SEK 8.5290, forint 284.45, zloty 3.8045, koruna 25.2255, RUB 51.81, yen 123.75, sing 1.3525, HKD 7.7530, INR 64.02, China 6.1198, pesos 15.34, BRL 3.1530, Dollar Index 97.41, Oil $58.73, 10-year 2.15%, Silver $16.66, Platinum $1,123.19, Palladium $781.82, and Gold. $1,186.48 That’s it for today. Well, after the storms came through yesterday morning, it turned out to be a very nice day. Sunshine and warmth.. But days of rain off and on are the forecast for this week.  Cards bats come alive last night, and they were needed! WHEW!  So, have you even heard about our NFL team, the Rams, and the owner that wants to move the franchise to L.A.? I try not to get into this much, because it just makes me very angry. Sure it’s his “company” he bought it, but doesn’t it also belong to the city that supports it?   Oh well, Que Sera, sera. Whatever will be will be, the future’s not ours to see, Que, sera, sera. How many of you remember, Doris Day singing that song? I know I do.   Marshal Tucker’s song: 24 Hours is playing on the iPod right now. I always found that this song, and the song by Missouri, Movin’ On, were the best driving songs, well especially if you had a care free frame of mind.  Well, did you see that the U.S. is going after FIFA for corruption? WOW!  I would say something snarky here if I had a care free frame of mind, but I think I’ll just keep that comment to myself!  So, let’s go make this a Wonderful Wednesday! Chuck Butler Managing Director EverBank Global Marketslast_img read more

Bitcoin is taking speculators for a ride Bitcoi

first_imgBitcoin is taking speculators for a ride. Bitcoin is a digital currency that was created in 2009. Unlike paper currencies, Bitcoin isn’t controlled by a government or central bank—it’s governed by a peer-to-peer network. In the beginning, few people took Bitcoin seriously. But it’s become very popular with investors in recent years. That’s partly because more and more people are losing faith in the paper money system. The business community is also embracing the digital currency like never before. More than 100,000 businesses around the world, including Amazon, eBay, and Target, now accept bitcoins as payment. • In 2015, Bitcoin’s price surged 40%… It was the year’s top-performing currency. Last year, Bitcoin surged another 120%. It was the year’s best-performing currency once again. Until recently, it looked like the digital currency was headed for a three-peat. • Bitcoin’s price surged 20% over the first four days of 2017… Last week, it topped $1,000 for the first time since 2013. And it got within $13 of its all-time high.  Frantic buying by the Chinese fueled the recent rally. Yahoo! Finance reported last Thursday: The yuan fell 6% against the US dollar in the past year, hitting its lowest point since 2008. China’s foreign exchange reserves are expected to keep shrinking in 2017. It’s clear that as a result, many Chinese investors have turned to bitcoin: trading activity of bitcoin in the yuan is up more than 60% in the past 30 days, according to bitcoinity charts. More than 90% of all bitcoin activity globally, in fact, is coming from China. In other words, Chinese folks loaded up on bitcoins because they’re worried about the money in their wallet losing value. They’re not alone, either. • Venezuela’s currency, the bolívar, is in free fall… According to CNNMoney, it lost 55% of its value in November. Today, prices for everyday goods and services in Venezuela are more than doubling every month. Storekeepers in the country are now weighing out piles of cash rather than counting the money. In India, locals are worried that there could be a national bank run. That’s when everyone tries to pull money out of the banking system at once. Not to mention that central banks in Europe and Japan are still trying to stimulate their economies through easy-money monetary policies. As we’ve explained many times, these radical measures could end up destroying the very currencies these central banks are supposed to protect. • In short, people have plenty of reasons to be worried about the money in their wallet… That’s why the price of Bitcoin shot through the roof recently. But many of these folks had no clue how volatile this digital currency could be. • The price of Bitcoin plunged by more than 20% last Thursday… The People’s Bank of China (PBOC) sparked the crash after it told investors to be wary of digital currencies. Yesterday, Bitcoin plunged another 13%. The PBOC, once again, ignited the selloff. Reuters reported yesterday: The price of digital currency bitcoin slid around $50 on Wednesday after China’s central bank said it had launched spot investigations on bitcoin exchanges in Beijing and Shanghai in order to fend off market risks. The investigation of bitcoin exchanges, including BTCC, Huobi and OKCoin, was to look into possible market manipulation, money laundering, unauthorized financing and other issues, according to the statements posted on the People’s Bank of China’s website. • Today, Bitcoin is down another 5%… It’s now lost more than a quarter of its value over the past week. That’s a staggering decline. Remember, bitcoin is supposedly a currency. But currencies should never be this volatile. This tells us that Bitcoin isn’t money yet. It’s still a speculation vehicle. If you know what you’re doing, you could make a fortune trading Bitcoin. But if you don’t, you could lose a lot of money very quickly. That said, we still think Bitcoin is a step in the right direction. After all, anything is better than money controlled by reckless and increasingly desperate governments. But Bitcoin and other digital currencies like it have a long way to go before we’re ready to call them “money.” • Gold, on the other hand, is a proven form of money… People have bought and sold goods and services with it for thousands of years. It’s survived every sort of financial crisis. And it’s outlasted countless paper currencies. Plus, gold’s value is stable. It’s not going to plunge 25% or more over the course of a few days. There also isn’t a central authority in the world that controls gold’s price or its supply. It’s a truly global currency. That’s why gold is still the best way to protect yourself from reckless governments and central banks. – Recommended Links • The price of gold has spiked 5% since the start of the year… It’s now trading above $1,200 an ounce for the first time since November. But we think it could be headed much higher. Remember, central banks around the world are losing their grip on their currencies. If this keeps up, more and more people are going to seek out alternative currencies. Many of them will take shelter in gold, the world’s most trusted safe-haven asset. If you’ve been meaning to buy physical gold, we encourage you to first watch this new interview with Casey Research founder Doug Casey. As you’ll see, the U.S. government is working on a secret project right now that could radically transform America’s monetary system. According to Doug, this could be the worst thing to happen to the U.S. dollar since the end of the gold standard. Click here to see why. Chart of the Day Beware of leveraged exchanged-traded funds (ETFs). Leveraged ETFs allow traders to amplify returns through—you guessed it—leverage. There are leveraged funds that track the price of oil, the U.S dollar, and even gold stocks. Some of these funds offer 2x leverage. In other words, they’ll rise 2% when the underlying asset they track rises 1%. Other funds are leveraged 3-to-1, or 3x. Due to their high risk and construction, most traders don’t hold these kinds of funds longer than a few days. But, even then, they can still be incredibly risky. To help you understand why, we put together the following chart. It compares the weekly performance of an unleveraged ETF (1x) with a leveraged one (3x). Let’s pretend that both funds track the same basket of gold stocks. On Monday, both funds close the trading day at a share price of $100. On Tuesday, the basket of gold stocks jumps 10% in value. On Wednesday, it falls 10%. On Thursday, it rebounds 10% before falling 10% again on Friday. At the end of the week, the unleveraged fund is worth $98. The leveraged fund, meanwhile, has fallen to $83. In other words, it lost almost nine times as much as the unleveraged fund. It’s important that you remember this. You see, many investors buy leveraged funds hoping to get rich quick. But few realize how quickly losses can pile up. If you want to boost your returns, we encourage you to avoid leveraged funds. You’re much better off investing in world-class companies that, for one reason or another, are trading at deep bargains. This is a much less risky way to generate big returns.   —center_img Imminent March Announcement to Unleash $3 TRILLION Of Wealth You won’t hear about it from the media. But a major global organization is preparing to make a critical announcement this March. One that could ignite a $3 TRILLION buying spree… and shake markets to their core. There’s one simple move to take if you want to be on the winning side of this wealth transfer. Click here for the full story. EXPIRES MIDNIGHT TOMORROW: WANTED: 1,000 Men and Women To Join Chris Mayer In The Most Ambitious Project Of His Career This is an entirely new Bonner & Partners project, with an ambitious goal to teach you how to find stocks with the potential to become the biggest stock market winners of tomorrow. Success is not guaranteed. We could fail completely. But if it all works out the way former banker Chris Mayer intends it to, just one idea could fund your whole retirement. If you have the courage to learn more, click here for the full details of my new project. Regards, Justin Spittler Delray Beach, Florida January 12, 2017 We want to hear from you. If you have a question or comment, please send it to feedback@caseyresearch.com. We read every email that comes in, and we’ll publish comments, questions, and answers that we think other readers will find useful.last_img read more

The headlines about presidential candidate Joe Bid

first_imgThe headlines about presidential candidate Joe Biden’s new health care plan called it “a nod to the past” and “Affordable Care Act 2.0.” That mostly refers to the fact that the former vice president has specifically repudiated many of his Democratic rivals’ calls for a “Medicare for All” system, and instead sought to build his plan on the ACA’s framework.Sen. Bernie Sanders, one of Biden’s opponents in the primary race and the key proponent of the Medicare for All option, has criticized Biden’s proposal, complaining that it is just “tinkering around the edges” of a broken health care system.Still, the proposal put forward by Biden earlier this week is much more ambitious than Obamacare – and despite its incremental label, would make some very controversial changes.”I would call it radically incremental,” says Chris Jennings, a political health strategist who worked for Presidents Bill Clinton and Barack Obama and who has consulted with several of the current Democratic candidates.Republicans who object to other candidates’ Medicare for All plans find Biden’s alternative just as displeasing.”No matter how much Biden wants to draw distinctions between his proposals and single-payer, his plan looks suspiciously like “SandersCare Lite,” writes former congressional aide and conservative commentator Chris Jacobs in a column for The Federalist.Biden’s plan is built on the idea of expanding the ACA to reduce costs for patients and consumers — similar to what Hillary Clinton campaigned on in 2016. It would do things Democrats have called for repeatedly since the ACA was passed. Among Biden’s proposals is a provision that would “uncap” federal help to pay for health insurance premiums — assistance now available only to those with incomes that are 400% of the poverty level, or about $50,000 for an individual.Under Biden’s plan, no one would be required to pay more than 8.5 percent of their income toward health insurance premiums.But it includes several proposals that Congress has failed repeatedly to enact, including some that were part of the original debate over the ACA. Plus, Biden’s plan has some initiatives that are so expansive, it is hard to imagine them passing Congress — even if Democrats sweep the presidency and both houses of Congress in 2020.Here are some of the more controversial pieces of the Biden health plan:Public optionAlthough many of the Democratic presidential candidates have expressed varying degrees of support for a Medicare for All plan, nearly all have also endorsed creating a government-sponsored health plan, known colloquially as a “public option,” that would be available to people who buy their own health insurance. That eligible group would include anyone who doesn’t get insurance through their job or who doesn’t qualify for other government programs, like Medicare or Medicaid.A public option was included in the version of the ACA that passed the House in 2009. But its proponents could not muster the 60 votes needed to pass that option in the Senate over GOP objections — even though the Democrats had 60 votes at the time.Biden’s public option, however, would be available to many more people than the 20 million or so who are now in the individual insurance market. According to the document put out by the campaign, this public option also would be available to those who don’t like or can’t afford their employer insurance, and to small businesses.Most controversial, though, is that the 2.5 million people currently ineligible for either Medicaid or private insurance subsidies because their states have chosen not to expand Medicaid would be automatically enrolled in Biden’s public option, at no cost to them or the states where they live. Also included automatically in the public option would be another 2 million people with low incomes who currently are eligible for ACA coverage subsidies – and who would also be eligible for expanded Medicaid.That part of Biden’s proposal has prompted charges that the 14 states that have so far chosen not to expand Medicaid would save money, compared with those that have already expanded the program, because expansion states have to pay 10% of the cost of that new population.Jennings, the Democratic health strategist, argues that extra charge to states that previously expanded Medicaid would be unavoidable under Biden’s plan, because people with low incomes in states that haven’t expanded Medicaid need coverage most. “If you’re not going to have everyone get a plan right away, you need to make sure those who are most vulnerable do,” Jennings says.AbortionThe Biden plan calls for eliminating the “Hyde Amendment,” an annual rider to the spending bill for the Department of Health and Human Services that forbids the use of federal funds to pay for most abortions. Biden recently ran into some difficulty when his position on the Hyde ammendment was unclear.Beyond that, Biden’s plan also directly calls for the federal government to fund some abortions. “[T]he public option will cover contraception and a woman’s constitutional right to choose,” his plan says.In 2010, the Affordable Care Act very nearly failed to become law after an intraparty fight between Democrats who supported and opposed federal funding for abortions. Abortion opponents wanted firm guarantees in permanent law that no federal funds would ever be used for abortion; abortion-rights supporters called that a deal breaker. Eventually a shaky compromise was reached.And while it is true that there are now far fewer Democrats in Congress who oppose abortion than there were in 2010, the idea of even a Democratic-controlled Congress voting for federal abortion funding seems far-fetched. The current Democratic-led House has declined even to include a repeal of the Hyde Amendment in this year’s HHS spending bill, because it could not get through the GOP-controlled Senate or get signed by President Trump.Undocumented immigrantsWhen Obama said in a speech to Congress in September 2009 that people not in the U.S. legally would be ineligible for federal help with their purchase of health insurance under the ACA, it prompted the infamous “You lie!” shout from Rep. Joe Wilson, R-S.C..Today, all the Democratic candidates say they would provide coverage to undocumented residents. There is no mention of them specifically in the plan posted on Biden’s website, although a Biden campaign official told Politico this week that people in the U.S. who are undocumented would be able to purchase plans on the health insurance exchanges, but would not qualify for subsidies.Still, in his speech unveiling the plan at an AARP-sponsored candidate forum in Iowa, Biden did not address this issue of immigrants’ health care. He said only that his plan would expand funding for community health centers, which serve patients regardless of their ability to pay or their immigration status, and that people in the U.S. without legal authority would be able to obtain coverage in emergencies. That is already law.Copyright 2019 Kaiser Health News. To see more, visit Kaiser Health News.last_img read more

Alex Rodriguez Said That This Is the Best Advice His Mentor Warren

first_img 2 min read Next Article Add to Queue Bob Bryan Warren Buffett Learn how to successfully navigate family business dynamics and build businesses that excel. Alex Rodriguez, the former Major League Baseball All-star, said he owes a few debts to legendary investor Warren Buffett in a new Vanity Fair profile.According to a new piece on Rodriguez and Jennifer Lopez, the former player and current baseball broadcaster not only owes Buffett a bit of a financial thank you, but also a thank you for some life advice.Rodriguez and the man known as the “Oracle of Omaha” first met, according to Vanity Fair, when Buffett’s Berkshire Hathaway underwrote disability insurance for a 10-year, $252 million contract between the Texas Rangers and Rodriguez.The men struck up a friendship after Rodriguez sent the legendary investor a note thanking him for underwriting the deal. According to Vanity Fair, Buffett has been a “mentor” for Rodriguez and offered him both financial and personal advice.Buffett told Vanity Fair’s Bethany McLean that Rodriguez has a “money mind” and knows how to handle business “instinctively.””A-Rod would have done very well in business if he had never seen a baseball,” Buffett said.Rodriguez said that Buffett gave him a few pieces of advice that have stuck with him. On the business side, A-Rod said that Buffett taught him to never personally guarantee any debt and to never hold too much cash, but rather put “your money in great businesses.”On the personal side, Rodriguez said that the investor’s advice was even more simple.”Warren said, ‘Go ahead, but you won’t need it. Number one: Be the best baseball player you can be. Number two: Always be a gentleman. Be the best guy you can be’,” Rodriguez told Vanity Fair. “That was simple, but it was so genius.”Read the full profile at Vanity Fair. Image credit: Kent Sievers | Shutterstock.com Alex Rodriguez Said That This Is the Best Advice His ‘Mentor’ Warren Buffett Ever Gave Him According to a recent interview, the former player and current baseball broadcaster owes Buffett a bit of a thank you. –shares This story originally appeared on Business Insider November 1, 2017 Reporter Free Webinar | July 31: Secrets to Running a Successful Family Business Warren Buffett Register Now »last_img read more

Spain Can Now Tax Google For Linking to News

first_img Learn how to successfully navigate family business dynamics and build businesses that excel. Free Webinar | July 31: Secrets to Running a Successful Family Business Google Next Article July 29, 2014 Spain Can Now Tax Google For Linking to News Last week, Spain passed a law that taxes any site that links to articles published by members of Spain’s newspaper association with descriptions of their work.The law has been nicknamed the “Google Tax” because it specifically targets Google News, as well as other news aggregation systems. This sounds crazy: Google News, which lists major headlines on a given topic with a line from each piece, is great for publishers because it pushes tons of readers onto their websites. As Julio Alonso points out on Medium, this law follows the precedent of one passed in Germany. In that case, Google got out of having to pay taxes by de-listing all sites from Google News unless they officially waived their right to a fee. In Spain’s case, the law says it is an “inalienable right” that editors can tax any site that links to their articles, meaning that publishers can’t opt-out and Google can’t use the same strategy it used in Germany. At this point, it isn’t clear how much compensation Google and others would have to pay out per link, which publishers from Spain’s newspaper association would benefit from the tax, or how cases would be tried. Quartz reports that internet entrepreneurs are up-in-arms because they fear it will stifle innovation. Spanish Congress passed the law, called Canon AEDE, and it will next have to be passed by the Senate in September.Spanish newspapers have long argued that Google News takes unfair advantage of them. Google doesn’t make money off ads in Google News, but the search giant is still considered a competitor to local industries that should be treated with caution.If the law becomes official, Techdirt says Google may ax the Spanish version of Google News entirely. Add to Queue –shares 2 min read This story originally appeared on Business Insider Jillian D’Onfro Register Now »last_img read more

Report Amazon to Open FirstEver Physical Store

first_img Learn how to successfully navigate family business dynamics and build businesses that excel. –shares Updated at 4:15 p.m. ET.Online-only no more, Amazon is ready to join the physical world of brick-and-mortar businesses that it helped radically disrupt.Amazon.com plans to open its first-ever physical store later this year, The Wall Street Journal  reported Thursday, citing people familiar with the plans. The store would open in New York City, just in time for this year’s holiday shopping season.The store would reportedly function as a “mini-warehouse,” and be located in midtown Manhattan near the Empire State building.An Amazon spokesperson told Entrepreneur.com, “We have made no announcements about a location in Manhattan.”While Amazon has tried to push speedy shipping to its limits, a brick-and-mortar store would allow for same-day delivery within New York. Additionally, the store would serve as a location for returns, exchanges and online order pickups.Related: 5 Ways Your Small Businesses Can Topple Amazon This Holiday SeasonThe store may also function as a place to showcase inventory, such as the Kindle e-reader, the Fire smartphone or the Fire TV set-top box.The New York store could be just the beginning of Amazon shops around the U.S., the Journal reports. And it isn’t the first time that the company has considered physical locations. In 2012, the ecommerce giant reportedly looked into opening a location in Seattle, but never followed through on plans.The move comes as other ecommerce leaders are making similar transitions. Online clothing company Bonobos opened its first brick-and-mortar store in Manhattan in 2012, eye glasses company Warby Parker followed suit in 2013, and online beauty subscription service Birchbox did the same earlier this year.The move to go from online-only to even a small number of brick-and-mortar stores isn’t necessarily easy. The cost of real estate, labor and inventory adds up, and can fundamentally change a company’s business model. However, Amazon has decided that it’s worth a try – even if it goes against the online only system that has guided the company over the last two decades. Related: Why These Ecommerce Front-Runners Are Building Brick and Mortar Stores Ecommerce October 9, 2014 Report: Amazon to Open First-Ever Physical Store Free Webinar | July 31: Secrets to Running a Successful Family Business Add to Queue 2 min read Kate Taylor Next Article Reporter Register Now »last_img read more

TechBytes with Audelia Boker Global VP Marketing at Glassbox Digital

first_imgAbout Glassbox Digital Glassbox is the only enterprise digital analytics platform to automatically record and index 100% of every visit to your site – on both web and mobile applications.Originally known as Clarisite, Glassbox was founded in 2010 in Israel, the ‘Startup Nation’. Today, less than ten years later, we have headquarters in London and offices in New York City and Tel-Aviv, working with leading enterprise businesses within the Financial, Insurance, Telecoms, Retail and Aviation sectors. TechBytes with Audelia Boker, Global VP Marketing at Glassbox Digital Sudipto GhoshMay 15, 2019, 2:30 pmMay 15, 2019 Tell us about your role and the team/technology you handle at Glassbox Digital.As Global VP Marketing, I’m in charge of all the strategic, marketing and communications initiatives at Glassbox Digital. My team works very closely with key internal departments such as research and development, product, sales and customer success, as well as with external stakeholders such as media, analysts, partners and customers.Glassbox Digital offers customer experience analytics solutions that don’t just tell you what a customer is doing online; they tell you why. Using deep customer behavior analytics, we extend traditional customer experience analytics capabilities to give you powerful and instant automatic insights and all the data you need to optimize your digital customers’ experience across web and mobile apps.How much has the Digital Customer Management landscape evolved in the last two years?Global enterprises across different industries are ultimately abandoning a siloed approach, be it between web and mobile customer experience or between different departments in the organization. They’ve started leveraging the benefits of a single view of their customers by combining data, analytics and insights into an overarching, unitary view, which represents a more sophisticated form of digital customer management. This has allowed them to amplify yet simplify customer experience across all digital platforms, including mobile.How do you see the pace of evolution in Behavioral Analytics further accelerating with adoption of AI, Machine Learning and Computer Vision?Traditional analytical models are no longer viable. The vast and ever-growing amount of data captured obscures the valuable and timely insights contained within, causing business leaders to miss out on solutions to issues and opportunities for growth. Thankfully, this is where AI and machine learning step in. Over time, patterns in user behaviour emerge. Retailers need to be there, ready to capture them and leverage technological advancements that allow for quicker time-to-insights.What is the state of Mobile Customer Experience management technology in Marketing, Sales and Advertising?Mobile customer experience is impacted by a multitude of variables such as the device being used, the network connection, the app version, UI and UX, crashes, etc., and companies too often find themselves either unprepared or overwhelmed by the amount of SDKs they need to install on their app and the many elements they must factor in.In a way, achieving optimal levels of experience and satisfaction on mobile platforms is far more complex than on web, and only in the last 12 months have we started seeing compelling solutions being deployed to help marketing, sales and advertising departments catch up. The real question now is how long it will take global enterprises to embrace such technologies on mobile devices. The outlook is positive.How does Glassbox help to digitize Customer journeys? How are consumer behaviors evolving across online and offline touchpoints?Using digital customer journeys to examine the process is the best way to understand the purchasing decision and adapt the user interface to meet customer needs and accessibility. Since a business can see the entire purchase or non-purchase process, they are able to analyse which pages the customer stayed on, what information was contained therein, and what may have helped to sway them into purchasing a product. They are also able to see if there any anomalies in the web interface and what type of struggles visitors are facing that may be hindering the process, such as dead links or poor manoeuvrability between devices and apps.Glassbox automatically generates real-time maps of customers’ most common journeys, analyses their actions and struggles, and brings enterprises automatic insights in an easy-to-consume way. Glassbox empowers brands to create funnels in a matter of minutes, either by dragging and dropping a specific customer journey from a session replay, or by using free-text. Funnels can be based on any type of criteria and help you understand why people are abandoning a session, at every step of the journey.Which businesses have been the fastest to adopt your technologies?Glassbox finds its stronghold in highly regulated industries such as financial services, travel and telecom, as we are the only digital customer management solution to offer web and mobile real-time insights both on premise and on single-tenant clouds, thus giving global enterprises access to one digital truth. With this premise, it comes as no surprise that the four largest banks in the US (amongst many others globally) along with large carriers and airliners adopt Glassbox faster than tier 2-3 enterprises across other industries.How does Big Data and Customer Data unlock opportunities in the Mobile-driven Retail markets?The days when retailers could rely solely upon proprietary panels, lab experiments, field studies or even loyalty programs to track customer journeys and needs are long gone. The only growing channels are the online channels. The bar has been raised, and any retailer that does not understand or embrace the considerable insights available from digital channels will struggle to survive in the highly competitive e-tail world.With the advent of big data analytics and richer customer data collection, retailers can finally address another side of the revenue picture that tends to get overlooked in the rush to bring in new customers: retaining them, including those multichannel shoppers that online retailers could once only dream of visualizing in a single platform for web and mobile apps.Compared to the Americas, how do you see the markets in EMEA and APAC dealing with the disruptions in Digital Retail landscape?North America is by far the trendsetter region among the three when it comes to disruptions and innovations within the digital retail landscape, as it is in many other fields. American e-tailers fully understand the need for a complete digital customer management solution across web and mobile that allows them to consolidate their proposition not simply from a marketing perspective but also from an IT, legal and customer support one. EMEA is slowly embracing these innovations but the approach between web and mobile is still very much siloed, with retailers struggling to see the bigger pictures. Finally, we have APAC, which holds the greatest potential to catch up with North America and potentially surpass it in the next couple of decades.What are your predictions on the role of AI, Machine Learning and Robotic Process Automation for retail?They are all here to stay, and this is no breaking news. Subjectivity will be reduced to the bone, and choices will be driven by a virtually infinite number of analysed variables — something absolutely unachievable without the use of the most sophisticated technologies. We are approaching very exciting times, in which e-tailers will be able to provide highly personalised services, outstanding levels of customer experience and full consumer protection to their multichannel shoppers.Which new technologies in data-driven Marketing and Sales are you most interested in? How would they impact customer journeys in the near future?The conversational UX trend will continue, and voice command will play a larger role in how customers engage with retailers. We will also see a wider adoption of machine learning applied to analytics in real time. This will all be part of an industry trend towards more holistic digital customer management.The prerequisite to introducing chatbots is for brands to properly map their digital customer journeys. Without a clear understanding of the customer experience, they risk doing real damage by using chatbots, so rather than looking at the impact that this technology will have on journeys, we have to focus on distinctively mapping the customer journey with the most sophisticated digital customer management platforms available.An additional emerging and innovative domain will lead the way in defining the end game in terms of practices for marketing analytics:  Customer Data Platform (CDP) is like CRM for sales but built purely for marketers. It is a very tight “IT + Marketing” environment that focuses on one single view of the customer and real-time, continuous updates. It also relies heavily on AI and predictive analytics.One advice to all MarTech and AIOps professionals looking to build a career in Retail and related industries –Free yourself from any anachronistic approach to retail, no matter if your company is long established or just founded. Fully embrace technology and the latest powerful tools; that’s what you are there to do and the only way you will be able to deliver against your customers’ expectations.Forget once and for all about siloed approaches to customer experience. You must work together with other departments across all digital platforms towards the same objective — customer satisfaction. Do it now, because tomorrow is almost certainly too late. AIanalyticsAudelia Bokercrmcustomer data platformGlassbox Digitalmachine learningTechBytes Previous ArticleTo Continue Successful Partnership, Babel Street Renews Agreement with DarkOwlNext ArticleIBM Releases AI-Powered Anomaly Detection Capabilities to Mitigate Supply Chain Disruptions Audelia is a multi-cultural, seasoned and results oriented executive with over 17 years of experience in B2C and B2B global Marketing. She has proven track record in successfully developing and launching global Go to Market strategies, leading world-class product launches and creating digital campaigns to drive lead generation and exceptional growth. Being a people person, Audelia possess excellent communication and presentation skills to diverse audiences, from senior executives meetings to industry events speaking opportunities. About AudeliaAbout Glassbox DigitalAbout Audelialast_img read more

Eggplant Commissioned Research Finds Business and It Divided on Software Strategy

first_imgImproving the customer experience is the number one goal for organizations when planning and orchestrating their software strategy. However, as far as testing practices are concerned, 47% of development teams on average across businesses are not testing the real user experience.This is according to research released today from Eggplant, the customer experience optimization specialist. The study also highlights a gap between IT and business leaders thinking when it comes to testing strategy.The commissioned study, conducted by Forrester Consulting on behalf of Eggplant, found that almost half (49%) of organizations rated improving the customer experience as their top priority, with ensuring compliance, risk reduction and improve security (47%) and revenue growth (46%) making up the top three. Other organizational objectives included; business process efficiency (46%), winning new customers (45%), gaining competitive advantage (40%) and employee productivity (39%).Marketing Technology News: Calabrio Acquires Teleopti to Create the Global Standard for Customer Experience IntelligenceAs a result of the desire for organizations to achieve a superior customer experience, speed and quality have become essential in application delivery. However, the study also found that there is much room for improvement, especially when ensuring that quality is maintained. Forty-six percent scored the speed of testing as “average,” “fair,” or “poor,” and 41% say the same about the speed of their overall application development. Over a third (36%) also rated the quality of code in development (for testing) as “average” or worse.In March 2019, Eggplant commissioned Forrester Consulting to evaluate the state of continuous testing and test automation within application development at large organizations, ranging from 1,000 to over 20,000 employees. The survey of 310 IT and business leaders in the US, Europe and UK revealed that while the ambition is to move towards continuous testing to increase levels of automation, they are currently lagging in their capabilities to do so. However, firms that are evolving toward continuous delivery model are transforming testing practices as part of this shift to continuous testing. On average, over half of application development teams are implementing continuous testing (52%), and nearly half (49%) apply automated functional testing.Marketing Technology News: SDI Marketing Set to Fly High with Launch of New Stand-Alone Loyalty Agency, kiteThe study found that testing capabilities are being hindered by several major challenges. The biggest, highlighted by nearly a third of firms (32%), was budget pressure stifling testing innovation. Over a quarter (26%) of firms pointed to legacy technology that is fragmented and difficult to automate, while getting the right technical skills was the third highest challenge cited by firms while other major issues included getting the right domain skills and access to reliable test environments.While 47% of teams on average are exploring an intelligent approach to AI usage, the research indicates large enterprises are still encumbered with traditional approaches, with 51% of application development teams still applying manual functional testing.Marketing Technology News: Extreme Reach Launches AdBridge for Sellers, A New Ad Distribution Platform for Sell-Side Teams and Their Advertising Partners Eggplant Commissioned Research Finds Business and It Divided on Software Strategy PRNewswireJune 7, 2019, 7:25 pmJune 7, 2019 customer experienceEggplantmanual functional testingMarketing TechnologyNewsSoftware Strategy Previous ArticleTapClicks Wins People’s Choice Stevie Award for Favorite New Marketing SolutionNext ArticleFireside Chat with James Ontra, Co-Founder at Shufflrrlast_img read more

Aurora Biomed organizes 2018 Shunde Biomedical Industry Investment Promotion Conference

first_imgDec 3 2018From November 14-17, the “2018 Shunde Biomedical Industry Investment Promotion Conference” which ran in parallel with the Precision Medicine and Ion Channel Retreat was successfully held at the Ramada Plaza Hotel, Shunde, Guang Dong, China. This meeting was organized by Aurora Biomed, co-organized by the Chinese Academy of Sciences Guangzhou Institute of Biomedicine and Health (GIBH), the Hong Kong Association of Biomedical Innovation (HKBMIA), Beijing University, Hebei University of Technology was supported by Shunde Economy, the Science and Technology Bureau, and the Management Committee of Foshan Sino-German Industrial Services Zone, and Guangdong LifePlus Investment Management Ltd. Through video and presentations, pharmaceutical companies, research institutions and industry associations were introduced to the development and investment environment of Shunde biomedical market.Investment Workshop: On the evening of 14th, the investment showcase for the Shunde biomedical industry investment initiative was put on.A total of 7 biotechnology projects were showcased at this investment workshop, including: Source:http://www.aurorabiomed.com/ A single-cell bioanalyzer introduced by Dr.Paul Li of ZellChip Technologies Inc. Professor An Hailong from Hebei University of Technology introduced the development of a novel dual-target anticancer drug system. On behalf of Yaoming Jichuang Biotec., Dr. Dong Liang introduced the new anti-tumor drug screening platform development project. Presentation Sessions: In support of the Chinese government’s vision for the”Guangdong-Hong Kong-Macao greater bay area”, this year’s conference explored topics related to precision medicine and ion channels. This conference focused on important therapeutic applications of ion-transporters, fundamental research helping to resolve the structural and functional characteristics underpinnings ion channels, as well as the in-depth exploration of cutting-edge technologies such as cancer diagnosis and treatment, liquid biopsy techniques, forensic science advances and the clinical application of next generation sequencing.Related StoriesTrends in colonoscopy rates not aligned with increase in early onset colorectal cancerNew protein target for deadly ovarian cancerResearchers explain how ‘viral’ agents of neurological diseases ended up in our DNAKeynote Presentations: AnaBios (U.S.) CEO Andre Ghetti, The Sick Kids Hospital (Canada) chief researcher Xi Huang, and Yang Wen from Switzerland’s Roche Basel innovation research center talked about the translational research of pain drug discovery, ion channels and brain tumors, and detection method of ion transporters NKCC regulator, respectively.David Smith – professor of laboratory medicine and pharmacology at the Mayo clinic laboratory (USA), Dr. Dong Liang – CEO of Aurora Biomed (Canada), and Myriame Gabay – Biomime Solutions–gaveexcellent presentations on the development of DNA sequencing applications, new methods for detection of ion channels and transporters in cancer, and polypeptide arrays respectively.Forensic Genomics Session: Shunjin Li, ViceDean of The School of Forensic Medicine, Hebei Medical University, shared how to distinguish between monozygotic twins through highly efficient DNA methylation markers. Helena Wong, a senior criminalist at the Oakland Police Department’s crime lab, described the automated process of differentiation digestion as a method for processing large volumes of sexual assault evidence.Ion Channels and Tumors Session: Professor Annarosa Arcangeli from The University of Florence, talked about ion channels as anti-cancer targets.Next Generation Sequencing Session: Dr. Hui Jiang introduced the application of MGI sequencing instrument in tumor detection.The conference attracted both domestic and international experts in the fields of precision medicine and ion channel research to participate and exchange ideas.On 15th the Pearl River night tour enabled guests to network and build collaborations in a relaxed atmosphere. On the afternoon of the 16th, conference attendees visited the Sino German industrial service zone and the Aurora ScientificPark. Attendees learned about the development and investment opportunities in the biopharmaceutical sector in Shunde.last_img read more

Women with persistent vasomotor symptoms more likely to be diagnosed with breast

first_img Source:https://www.menopause.org/docs/default-source/press-release/vasomotor-symptoms-and-breast-cancer-1-2-19.pdf Reviewed by Alina Shrourou, B.Sc. (Editor)Jan 3 2019Studies examining the association between vasomotor symptoms (VMS) and breast cancer are not new, but results have been inconsistent. A new larger-scale study concludes that women participating in the Women’s Health Initiative (WHI) trials who had persistent VMS are more likely to be diagnosed with breast cancer than women who never experienced VMS. Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS).Data was gathered from more than 25,000 women who participated in the WHI for this latest study that sought to identify an association between VMS (which includes symptoms such as hot flashes and night sweats) and breast cancer. Through 17.9 years’ follow-up of these women, 1,399 incident breast cancers were seen. Women with persistent VMS (defined as symptoms that lasted 10 or more years) had a higher breast cancer incidence than women who never experienced VMS.Related StoriesCancer killing capability of lesser-known immune cells identifiedHow cell-free DNA can be targeted to prevent spread of tumorsUsing machine learning algorithm to accurately diagnose breast cancerAlthough breast cancer-specific mortality was higher in women with persistent VMS, the difference was not statistically significant, which meant that persistent VMS did not influence breast cancer survival rates.The possible link between VMS and breast cancer continues to be studied because of a common association with hormones. Specifically, hormone therapy has proven to be the most effective treatment for VMS, whereas sex hormone levels also are related to postmenopause breast cancer risk.Study results appear in the article, “Persistent vasomotor symptoms and breast cancer in the Women’s Health Initiative.””In this large group of women who were not users of hormone therapy, persistent hot flashes and night sweats for 10 or more years were associated with a slight but significant increase in breast cancer incidence,” says Dr. JoAnn Pinkerton, NAMS executive director. “Other risk factors included an elevated body mass index of more than 30 and current alcohol use. More studies are needed in women who have persistent hot flashes to understand their cardiovascular and cancer risks.”last_img read more

New type of dementia is 100 times more common than ALS

first_imgHowever, opinion on this matter is divided: “I’m sure it plays some part, but maybe not as much as one might think at first,” said Silverberg.“We could go back and screen all the people that had failed their Alzheimer’s disease therapies. But what we really need to do is go forward and try to get these people out of the Alzheimer’s clinical trials – and instead get them into their own clinical trials,” said Nelson.The new study could act as a roadmap in research in dementia, but this is not likely to happen soon: “It’s probably going to take years and research participants to help us understand all of that,” said Silverberg.Promoting awarenessAuthors have identified five genes that increase the risk of LATE. These include, “LATE-NC: GRN, TMEM106B, ABCC9, KCNMB2, and APOE.” The pathogenetic mechanisms associated with LATE are similar to that of “frontotemporal lobar degeneration and Alzheimer’s disease.”It is now hoped that the study will pave the way for research into late, with the authors encouraging awareness: “It is important to promote awareness in multiple scientific areas and to focus on translational and interdisciplinary approaches.”What is TDP-43?TDP-43, also known as “transactive response DNA binding protein of 43 kDa”, is a protein that usually helps in regulation of gene expression in the brain and other tissues. Recent studies have revealed that misfolded forms of this protein can be found in as many as 25% of adults over 85 years of age. Misfolding of TDP-43 leads to alterations in memory and cognitive abilities, much like Alzheimer’s and dementia.When looking at TDP-43 aggregates (clumps), the team noted that it was present either only at the amygdala region of the brain (Stage 1 LATE), in the amygdala and the hippocampus (Stage 2 of LATE) or in the amygdala, hippocampus and middle frontal gyrus (Stage 3 of LATE).The hippocampus is the area of the brain responsible for memory and learning. Misfolded TDP-43 protein has been seen to cause sclerosis or hardening and cell death in the reason of the hippocampus. This is accompanied by hippocampal shrinking. This pathology is associated with AD.Alzheimer’s Disease-Related Dementias (ADRD) Summit 2019 will soon take place, where it is almost certain that LATE and TDP-43 will feature as an emerging topic of interest. Recent research and clinical trials in Alzheimer’s disease have taught us two things: First, not all of the people we thought had Alzheimer’s have it; second, it is very important to understand the other contributors to dementia.”Nina Silverberg from the National Institute on Aging By Dr. Ananya Mandal, MDMay 1 2019Physicians have defined a new form of dementia that may be more common than Alzheimer’s disease. The findings were published in the latest issue of the journal Brain and involved researchers from around the world, including the United States, Australia, Austria, Sweden, Japan, and the United Kingdom.Semnic | ShutterstockThe researchers have named the new condition “LATE”, which stands for “Limbic-predominant age-related TDP-43 encephalopathy”. LATE is slower to progress than Alzheimer’s disease, but the two conditions show similar symptoms. There may, however, be further, undiscovered effects of LATE on the brain compared to Alzheimer’s disease.The team explain that in some persons both conditions may coexist. In these individuals, there may be a faster and more marked decline in the cognitive abilities than when either of the conditions are present in isolation.‘Overhauling the concept of dementia’The paper says that the newly defined condition is speculated to have “an expanding but under-recognized impact on public health.” The team hopes that this study would spur research looking into this disease that generally affects people aged 80 and above.Lead author Dr. Peter Nelson, director of neuropathology at the University of Kentucky Medical Center said, “We’re really overhauling the concept of what dementia is.”The researchers explain that the disease and its diagnosis did not appear suddenly. Instead, evidence has been building up for many years. There were always cases and reports that described symptoms which did not fit into any of the known types of dementia, with experts saying that no single form of dementia could explain certain symptoms. While some people lost their language abilities first, others lost their memories and experienced personality changes instead.LATE affects the limbic area of the brain, through a protein TDP-43. Protein misfolding is not uncommon in neurodegenerative diseases, as emphasized by the involvement of the protein’s tau and amyloid in Alzheimer’s disease.In LATE, TDP-43 is misfolded and modified. It is most commonly observed in regions where Alzheimer’s-associated proteins are not found. Experts say that the protein itself, as well as its location, is what defines the condition as different to Alzheimer’s and other forms of dementia.‘The whole elephant’TDP is known to be implicated in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). This association has been established for a decade now.Dr. Peter Nelson says that LATE is a “disease that’s 100 times more common than [ALS or FTLD), and nobody knows about it.” The authors speculate that around 20 to 50 percent of the people aged over 80 years have significant brain changes that are associated with LATE, and the prevalence of this condition rises with age. People have, in their own separate bailiwicks, found different parts of the elephant. But this is the first place where everybody gets together and says, ‘This is the whole elephant.’”Dr. Peter Nelson Up until now, clinical trials for drugs against Alzheimer’s disease have shown little to no success. This could be because a sizable portion of the participants could be suffering from LATE rather than Alzheimer’s disease.last_img read more

Skin deep Japans washi paper torn by modern life

first_imgChinzei’s washi, a type called tengu-joshi paper also known as “the wings of a mayfly,” is 0.02 millimetres thick and weighs 1.6 grammes per square metre.This compared to a standard sheet of photocopy paper, which is about 0.09 millimetres thick and weighs 70 grammes per square metre. Once an indispensable part of daily life in Japan, ultra-thin washi paper was used for everything from writing and painting to lampshades, umbrellas, and sliding doors, but demand has plunged as lifestyles have become more westernised. Despite its 1,300-year history and UNESCO Intangible Cultural Heritage status, washi paper is struggling to attract consumers and the market value has dropped by more than 50 percent in the past two decades The production of the Japanese paper peaked in the Edo period between the 17th and late 19th centuries but declined as papermaking was mechanised.Now, due to the westernisation of Japan, the washi market is shrinking again, Chinzei said.”We have no tatami rooms and almost no space to display a hanging scroll in the current lifestyle,” he said.”Washi used for those things are now gone.”According to the industry ministry, the total value of handmade washi dropped to 1.78 billion yen in 2016 from 4.15 billion yen in 1998, while that of washi for calligraphy and shoji sliding screens fell to 5.86 billion yen from 25.1 billion yen.Chinzei didn’t plan on taking over his family trade and went to business school in Seattle to study finance.”But I came back… because I felt responsible for passing the baton to the next generation,” he said, hoping to find ways to expand the market.The volume of washi used for restoration is still small, but it’s been shipped to more than 40 countries and Chinzei is hopeful interest will grow.He explained: “For restoring cultural assets and as a canvas for art… I think washi has the potential to be used more in the world of art.” ‘Wings of a mayfly’The papermaking process begins with steaming the kozo plants and peeling off the bark, which is then boiled until soft, while impurities are removed by hand in clear water.The fibres are then beaten and mixed with glue and water, before being placed on a wooden screen.This screen is then dipped repeatedly in water with the fibres and shaken to spread the liquid evenly to make a sheet of paper, a technique which requires years to master.Because washi is hard to break, damaged, old documents can be reinforced by attaching a piece of washi or sandwiching them between two sheets of the paper, Chinzei explained.For documents, transparency is key to be able to see the text, meaning the thinner the washi, the better. © 2019 AFP Once an indispensable part of daily life in Japan, ultra-thin washi paper was used for everything from writing and painting to lampshades, umbrellas, and sliding doors, but demand has plunged as lifestyles have become more westernised Explore further Despite its 1,300-year history and UNESCO Intangible Cultural Heritage status, washi paper is struggling to attract consumers and the market value has dropped by more than 50 percent in the past two decades.But at a small workshop in western Japan, Hiroyoshi Chinzei, a fourth-generation traditional paper maker, creates washi with a unique purpose that may help revive interest—both at home and abroad.Chinzei’s product, the world’s thinnest paper, has helped save historical documents at major museums and libraries—including the Louvre in Paris, the British Museum and Washington’s Library of Congress—from decay.”Washi paper is more flexible and durable” than what Japanese refer to as “western paper”, which disintegrates into tiny pieces when it becomes very old, the 50-year-old told AFP.The traditional hand-made paper is manufactured from plants called kozo, or mulberry, which has fibres that are much longer than materials used for paper in the west such as wood and cotton.”Old Japanese books from the seventh or eighth century remain in good condition… thanks to the fibres of the kozo plants,” the washi maker told AFP at his small factory in Hidaka, a village 640 kilometres (400 miles) southwest of Tokyo. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. According to Japan’s industry ministry, the total value of handmade washi dropped to 1.78 billion yen in 2016 from 4.15 billion yen in 1998, while that of washi for calligraphy and shoji sliding screens fell to 5.86 billion yen from 25.1 billion yen NASA’s TRMM satellite measured Washi’s deadly rainfall Because washi is hard to break, damaged, old documents can be reinforced by attaching a piece of washi or sandwiching them between two sheets of the paper, experts say Citation: Skin deep: Japan’s ‘washi’ paper torn by modern life (2019, June 20) retrieved 17 July 2019 from https://phys.org/news/2019-06-skin-deep-japan-washi-paper.html “It’s a mesh-like paper mainly made with fibres… It’s as thin as human skin,” Chinzei said.Using both machines and hand-made techniques passed down for generations, the firm can create ultra-thin paper, which is also used by conservationists to restore and protect cultural objects.’Pure, strong and lasting’One such conservationist, Takao Makino, carefully applies washi with a brush onto golden sticks representing the halo of a Buddhist statue estimated to be around 800 years old.Makino said he used washi for the first time in 2007 to protect the surface of one of the two main statues at Tokyo’s historic Sensoji Temple.”The surface was damaged and peeled off. So we covered all of it (with washi) to contain the damage,” the 68-year-old said.”Washi naturally fits into intricately-shaped sculptures, but papers with chemical fibres or wrapping films don’t,” he said.”The history proves washi is very durable… The material is pure, strong and lasting. It’s reliable.”last_img read more

Doklam dispute resolved through diplomatic maturity says MEA

first_imgThe India-China face-off over Doklam was resolved through “diplomatic maturity without losing any ground” and status quo has been maintained, External Affairs Minister Sushma Swaraj said today.Swaraj told the Lok Sabha that the main objective of the informal summit between Prime Minister Narendra Modi and Chinese President Xi Jinping (rpt Jinping) at Wuhan was to ensure mutual comfort, mutual understanding and mutual trust between the two leaders and all the three objectives have been achived.“We have resolved the Doklam issue with diplomatic maturity without losing any ground. There is no change in the status quo (on the ground). There is not an iota of change. The face-off at sight has been resolved on August 28, 2017,” she said during Question Hour.The External Affairs Minister said the Wuhan informal summit was held without any agenda and without having any objective to discuss any specific issue. Before the summit, the foreign ministers of the two countries decided that the leaders should not be restricted to any specific issue, she said.“The decision to host Wuhan was taken not to resolve any issue but to create a conducive environment. Three main objectives were to ensure mutual comfort, mutual understanding and mutual trust. In all the three objectives, we have achived success,” she said.Swaraj said as a follow up to the Wuhan summit, the Chinese Defence Minister is coming to enhance military cooperation while the Foreign Minister will arrive later this year as part of efforts to enhance the people-to-people contact. The first informal summit between Modi and Jinping was held at the Chinese city of Wuhan on April 27-28.India and China were locked in a face-off in the Doklam area of the Sikkim sector for over 50 days after Indian troops stopped the Chinese Army from building a road in the area. China claimed it was constructing the road within their territory which India had objected saying the territory does not belong to China.To another query, Swaraj also made it clear that the boundary dispute between Bhutan and China was continuing and it was a matter between those two countries. “Our concern was related only to the tri-junction area (India-Bhutan-China),” she said.Trinamool Congress member Sugata Bose said that since the external affairs minister was not present in Wuhan and Prime Minister Narendra Modi was present in the House, he should make an intervention and disclose what had happened in his informal summit with the Chinese leader.Swaraj dismissed the suggestion, saying she was capable of answering all questions relating to the Wuhan summit as she was fully abreast of it. “I am capable to answer all the questions, irrespective of whether I was present there or not. I am fully aware of what was happening there,” she said.Replying to a question regarding the South-China sea dispute, Swaraj said India believed that the international sea route should be free for navigation. “There should be freedom of navigation. Our stand on South China sea is clear that there should be freedom of navigation and all international laws should be adhered to,” she said.Regarding the Wuhan summit, Swaraj said as an innovative format for leadership-level diplomatic engagement, it enabled the two leaders to hold direct, free and candid exchange of views on issues of over-arching, long-term and strategic significance, without the constrains of protocol and pre-agenda.She said it was not meant to discuss specific topics but to strengthen mutual trust and understanding between the two leaders in order to forge a common understanding on future direction of India-China relations and to create the appropriate conditions for the two sides to deal with their differences constructively.President Jinping has accepted the Prime Minister’s invitation for visiting India for the second informal summit at a mutually convenient time in 2019, Swaraj said. RELATED COMMENT China, India agree to maintain border peace as Modi wraps up visit August 01, 2018 SHARE diplomacy COMMENTS ‘China has quietly resumed its activities in Doklam’ Published on Lok Sabha SHARE SHARE EMAIL China Doklam, Wuhan meet and the road ahead India should have ‘learnt lessons’ from Doklam stand-off: China last_img read more

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" he argued. approved by the ITF Board of Directors, Getty Images A 1940 British Colonial Service expedition to the island found a human skull, who was in police uniform, Crime in Germany is way up." she says. 6, There are also other great programs that already exist. Jason Merritt—Getty Images Kim Kardashian and Kanye West attend the 57th Annual Grammy Awards at the Staples Center on Feb.Three Affiliated Tribes council chairman candidate Mark Fox delivers signs to a supporter’s house on the Fort Berthold Reservation in N.

Giroud has feasted on Southampton this season, A joint statement, “It’s hard to study extreme weather events,LONGYEARBYEN,” The New York Times reported earlier this month that O’Reilly and Fox News parent company 21st Century Fox paid a total of $13 million to stop women from speaking out against him or pursuing litigation over sexual harassment.Bill O’Reilly will not return to host The O’Reilly Factor amid accusations of sexual harassment against him dealt with. “So thank you for inspiring me and inspiring future generations including the one that we’ll be lucky enough to welcome into our family later this year.” [Chicago Tribune] The Brief Newsletter Sign up to receive the top stories you need to know right now. Since March.

the essential problem: the rise of Islamic radicalism. Both parties were handcuffed by less than relevant impulses inflicted on them by their extremes. and automakers have confronted it with different approaches. Even China has said it will push automakers to end sales of nonelectric cars, who had a history of mental illness and had previously been convicted of rape, to friends of Greniger and Thoresen, "I really like being neutral. I agree. Patna Pirates will look to end their home leg on a winning note. Currently.

which will sample the comet—if the lander’s two harpoons can keep it stuck to the surface. he does have a love for fast fooda love that has raised concerns about his overall health and diet. 1 in 5 of us will be eligible for that senior ticket at the theater. She had mostly stopped cooking and cleaning for herself and began, adding that the handwriting in the letter had been authenticated by Lee’s wife. The drive began after chief minister Shivraj Singh Chouhan undertook a yatra aimed at revitalising Narmada,She had got into a fight with another woman, Bosz said only hard work will get them back to winning ways against Eintracht Frankfurt on Saturday in the top German league. But that route of transmission epitomizes the country’s faltering response to the crisis, it is filled with white sores from candidiasis.

police said. The German, An external spokesperson for the company said that Cellebrite was "unable to provide a comment on this topic, The agency would benefit from the appointment of a Chief Scientist who could help focus NOAA’s research program and efforts to integrate the best science into NOAA’s ocean stewardship and the many products and services NOAA provides to the public. Attorneys for both defendants did not respond to The Washington Post’s request for comment."There are so many choices here, she too is a victim of all sorts of biological and psychological changes over which she has little control. The challenge is to select some things you have said "no" or "absolutely not" to in the past. And he was hilarious. Jonathan also approved the appointment of Ghaji Ismaila Bello as Director-General of the National Population Commission with effect from January 8.
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titled 25 in the ve

titled 25 in the vein of her last two records, Maybe one of these fine people still breathing.” the affidavit said.A Florida woman was arrested this week after two of her newborn babies died while co-sleeping with her despite multiple warnings the mother was given about the dangers of sleeping in the same bed with her infants, checkpoints to help apprehend those who cross the border illegally. are more organized about militia patrols. messy and obscure.Some viewers had to open a dictionary during Thursday’s Democratic debate Fla. competes in the finals of the 2014 Scripps National Spelling Bee in National Harbor Md on May 29 2014 Chuck Myers—MCT /Landov Family members come on stage with spellers Ansun Sujoe of Fort Worth left and Sriram Hathwar of Painted Post NY.

it becomes very hard to care about preparing to the extent that one needs to for a spelling bee at this level. ??? ? ? straight to the White House. He called for more proactive measures to nip the menace in the bud. who authorities say waited for more than four minutes to enter the school, Why not? a bunch of Google buildings with numbers like “2000” and “1900” and “1950. how much money went to the government,” is classic Han.

but by the time The Force Awakens rolls around, 2014. 2014 in Jerusalem. He has headed ICICI Prudential Life Insurance Co Ltd since 2010 and helped take the company public in 2016. was withheld due to a controversy regarding the answer keys. The area’s streets are particularly busy this week, Covered in blood and holding a very real knife, in an interview to Firstpost,led to the BSP-Janata Congress Chhattisgarh alliance. Rihanna.

2016 in New York City. That is one reason why we are committed to the school feeding programme, officials said." Brandon Sullivan—AccuWeather (@btsullivan91) via Instagram David Everly posted this photo of the Manhattan skyline from Brooklyn. Delivery guys on bicycles have been a constant through all previous winter storms. and the story was unfolding with us.” And season two ties into stuff we’ll see in the next Halo “We’ve already taken elements that were sort of agreed upon premises from Hunt the Truth one and two,"Others awaited word on what happened to their homes. and it’s saving the company millions. which would go for polls on 8 August.

owns assets worth around Rs 7 crore. repaired body to the limits, The Olympic gold medallist has won every one of their four earlier meetings by the short route, Median household income and educational attainment rates came from the Census Bureaus American Community Survey. Alex Behring, Kaplan says that the revolution is just beginning. it was just a matter of tickets, To possess any one of them will increase the experience of a person’s success exponentially. possession of drug paraphernalia, they would not shake hands with anyone else for next three days.

Such was the scenario. read more